藥物交互作用
Eslicarbazepine + Rilpivirine
嚴重程度: 禁忌併用
Eslicarbazepine and Rilpivirine: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Eslicarbazepine can lower rilpivirine concentrations via CYP3A4 induction. This may cause loss of virologic suppression and NNRTI resistance.
用白話說明這項交互作用的意義
Eslicarbazepine and Rilpivirine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eslicarbazepine belongs to Central Nervous System; Rilpivirine belongs to Anti Virals.
為什麼會發生
Eslicarbazepine induces CYP3A4, increasing the metabolism of rilpivirine.
處置方式
Avoid the combination. Use a non-inducing antiseizure drug or an alternative antiretroviral regimen.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Eslicarbazepine 的其他交互作用
Rilpivirine 的其他交互作用
常見問題
Can I take Eslicarbazepine with Rilpivirine?
MediHelp rates the interaction as contraindicated. Eslicarbazepine and Rilpivirine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eslicarbazepine can lower rilpivirine concentrations via CYP3A4 induction. This may cause loss of virologic suppression and NNRTI resistance.
How serious is the interaction between Eslicarbazepine and Rilpivirine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Use a non-inducing antiseizure drug or an alternative antiretroviral regimen.
What other medicines interact with Eslicarbazepine?
MediHelp also lists interactions of Eslicarbazepine with, for example, Mavacamten, Artemether / lumefantrine, Avapritinib. The full list is on the Eslicarbazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
