藥品參考
Risankizumab
Risankizumab is a medicine in the class miscellaneous. It is used for crohn's disease.
- 藥物類別: Miscellaneous
- 用途: crohn's disease
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- L04AC18
- 常見劑型
- 注射劑
- 常見規格
- 150 mg/ml
- 已知交互作用
- 2 (嚴重: 1 · 中度: 1)
- 商品名
- 3
- 國家與市場
- 3
用途
作用方式
Humanized IgG1 monoclonal antibody that selectively binds the p19 subunit of human IL-23 and inhibits its interaction with the IL-23 receptor, reducing release of pro-inflammatory cytokines and chemokines.
成人常用劑量（仿單摘要）
Plaque psoriasis: 150 mg, subcutaneous injection, at Week 0, Week 4, and every 12 weeks thereafter
懷孕與哺乳
- 懷孕
- Unknown Data are insufficient to show a risk; a registry exists. Antibodies cross the placenta, mainly late in pregnancy, and may suppress the infant's immunity. Monkeys had more fetal and infant deaths at high doses. Use only if needed; delay live vaccines in exposed infants.
- 哺乳
- Safe No human milk data. A large antibody: milk levels are likely very low and it is probably digested in the infant's gut. Some expert guidelines consider it acceptable while breastfeeding (LactMed). US label: weigh benefits.
已通報的副作用
- Upper respiratory infections
- Headache
- Fatigue
- Injection site reactions
- Tinea infections
- Arthralgia
禁忌症
- History of serious hypersensitivity reaction to risankizumab-rzaa or any excipients.
哪些人需要特別留意
- Serious hypersensitivity reactions including anaphylaxis may occur; discontinue and treat immediately if it occurs.
- May increase risk of infection; do not start in clinically important active infection and withhold if one develops until resolved.
- Evaluate for TB before initiating; do not give to patients with active TB; monitor for TB signs during and after treatment.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (2)
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Risankizumab 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
相關快速閱讀
常見問題
What is Risankizumab used for?
Risankizumab is a medicine in the class miscellaneous. It is used for Crohn's disease, Plaque psoriasis, Psoriatic arthritis, Ulcerative colitis.
What side effects have been reported with Risankizumab?
Upper respiratory infections, Headache, Fatigue, Injection site reactions, Tinea infections, Arthralgia.
Can Risankizumab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Data are insufficient to show a risk; a registry exists. Antibodies cross the placenta, mainly late in pregnancy, and may suppress the infant's immunity. Monkeys had more fetal and infant deaths at high doses. Use only if needed; delay live vaccines in exposed infants. Breastfeeding: Safe. No human milk data. A large antibody: milk levels are likely very low and it is probably digested in the infant's gut. Some expert guidelines consider it acceptable while breastfeeding (LactMed). US label: weigh benefits.
What does Risankizumab interact with?
MediHelp lists 2 known interactions for Risankizumab. Major: 1 · Moderate: 1. The most serious include Upadacitinib, Measles mumps and rubella vaccine.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
