藥品參考
Sevelamer
Sevelamer is a medicine in the class miscellaneous. It is used for serum phosphorus regulation.
- 藥物類別: Miscellaneous
- 用途: serum phosphorus regulation
最後更新
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重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- V03AE02
- 常見劑型
- 錠劑, 口服懸液
- 常見規格
- 800 mg, 2.4 g
- 已知交互作用
- 19 (中度: 8 · 輕微: 11)
- 商品名
- 18
- 國家與市場
- 5
用途
作用方式
Polymeric phosphate binder; decreases serum phosphate concentrations without changing calcium, aluminum, or bicarbonate concentrations
成人常用劑量（仿單摘要）
Initial dose: 1600 mg PO q8hr with meals
懷孕與哺乳
- 懷孕
- Safe Not absorbed from the gut, so the fetus is not exposed. It can lower folic acid and fat-soluble vitamins; consider supplements. EU label: give in pregnancy only if clearly needed (rat toxicity at high doses).
- 哺乳
- Safe Not absorbed, so it does not reach milk or the infant (US label, LactMed). Acceptable while breastfeeding. The mother may need vitamin and folate supplements.
已通報的副作用
- Vomiting
- Diarrhea
- Nausea
- Dyspepsia
哪些人需要特別留意
- Monitor serum bicarbonate and chloride levels
- Tablets should not be crushed, broken, or chewed (tablets rapidly expand and become a choking hazard)
- Caution in dysphagia, GI motility disorders, GI surgery
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (19)
- Carbamazepine + Sevelamer Moderate
- Ciprofloxacin + Sevelamer Moderate
- Dichlorphenamide + Sevelamer Moderate
- Erdafitinib + Sevelamer Moderate
- Gabapentin + Sevelamer Moderate
- Mycophenolic acid + Sevelamer Moderate
- Roxadustat + Sevelamer Moderate
- Sevelamer + Vadadustat Moderate
- Amiodarone + Sevelamer Minor
- Diazepam + Sevelamer Minor
常見問題
What is Sevelamer used for?
Sevelamer is a medicine in the class miscellaneous. It is used for Serum phosphorus regulation.
What side effects have been reported with Sevelamer?
Vomiting, Diarrhea, Nausea, Dyspepsia.
Can Sevelamer be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not absorbed from the gut, so the fetus is not exposed. It can lower folic acid and fat-soluble vitamins; consider supplements. EU label: give in pregnancy only if clearly needed (rat toxicity at high doses). Breastfeeding: Safe. Not absorbed, so it does not reach milk or the infant (US label, LactMed). Acceptable while breastfeeding. The mother may need vitamin and folate supplements.
What does Sevelamer interact with?
MediHelp lists 19 known interactions for Sevelamer. Moderate: 8 · Minor: 11. The most serious include Carbamazepine, Ciprofloxacin, Dichlorphenamide.
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