藥物交互作用
Ciprofloxacin + Sevelamer
嚴重程度: 中度
Ciprofloxacin and Sevelamer: moderate interaction.
最後更新
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摘要
Sevelamer binds oral ciprofloxacin in the gut and markedly lowers its absorption. This can result in subtherapeutic antibiotic levels and treatment failure.
用白話說明這項交互作用的意義
Ciprofloxacin and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Sevelamer belongs to Miscellaneous.
為什麼會發生
Binding of ciprofloxacin to sevelamer in the gastrointestinal tract reduces its absorption.
處置方式
Give oral ciprofloxacin at least 2 hours before or 6 hours after sevelamer. Monitor for clinical response to the infection.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ciprofloxacin 的其他交互作用
Sevelamer 的其他交互作用
常見問題
Can I take Ciprofloxacin with Sevelamer?
MediHelp rates the interaction as moderate. Ciprofloxacin and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sevelamer binds oral ciprofloxacin in the gut and markedly lowers its absorption. This can result in subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Sevelamer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after sevelamer. Monitor for clinical response to the infection.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
