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藥物交互作用

Mycophenolic acid + Sevelamer

嚴重程度: 中度

Mycophenolic acid and Sevelamer: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Sevelamer can reduce mycophenolic acid absorption, lowering exposure and potentially compromising immunosuppression in transplant recipients.

用白話說明這項交互作用的意義

Mycophenolic acid and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Mycophenolic acid belongs to Miscellaneous; Sevelamer belongs to Miscellaneous.

證據等級: Moderate

為什麼會發生

Binding of mycophenolate in the gut by the phosphate binder reduces absorption.

處置方式

Take mycophenolic acid at least 2 hours before sevelamer. Watch for rejection and consider checking MPA exposure.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Mycophenolic acid with Sevelamer?

MediHelp rates the interaction as moderate. Mycophenolic acid and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sevelamer can reduce mycophenolic acid absorption, lowering exposure and potentially compromising immunosuppression in transplant recipients.

How serious is the interaction between Mycophenolic acid and Sevelamer?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take mycophenolic acid at least 2 hours before sevelamer. Watch for rejection and consider checking MPA exposure.

What other medicines interact with Mycophenolic acid?

MediHelp also lists interactions of Mycophenolic acid with, for example, Activated charcoal, Azathioprine, Cholestyramine. The full list is on the Mycophenolic acid page.

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