藥品參考
Tobramycin
Tobramycin is a medicine in the class anti bacterial. It is used for bacterial infections.
- 藥物類別: Anti Bacterial
- 用途: bacterial infections
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- ATC 代碼
- J01GB01
- 常見劑型
- 滴劑, 軟膏, 溶液, 注射劑, 膠囊
- 常見規格
- 0.3%, 20 mg/2 ml, 28 mg
- 已知交互作用
- 141 (禁忌併用: 1 · 嚴重: 41 · 中度: 75 · 輕微: 24)
- 商品名
- 41
- 國家與市場
- 5
用途
作用方式
Inhibits protein synthesis by irreversibly binding to bacterial 30S and 50S ribosomes
成人常用劑量（仿單摘要）
Bacterial Infections: 3-6 mg/kg/day IV/IM divided q8hr OR 4-7 mg/kg/dose IV/IM qDay
懷孕與哺乳
- 懷孕
- Unsafe Injection: aminoglycosides can cause fetal harm; streptomycin has caused permanent congenital deafness. Use only for serious infections with drug-level monitoring. Inhaled form gives minimal absorption. Eye/ear drops: little absorbed; acceptable.
- 哺乳
- Safe Poorly excreted into milk; infant blood levels are far below treatment levels. LactMed: acceptable; watch for diarrhoea, thrush or nappy rash. Inhaled tobramycin is compatible (respiratory experts); eye or ear drops pose little or no risk.
已通報的副作用
- Neurotoxicity
- Increased lacrimation
- Nephrotoxicity
- Itching and edema of eyelid
- Ototoxicity
禁忌症
- Documented hypersensitivity to any aminoglycoside or history of hypersensitivity or serious toxic reactions to aminoglycosides
哪些人需要特別留意
- Monitor serum aminoglycoside concentrations if concurrent systemic aminoglycoside therapy is in progress
- May result in overgrowth of nonsusceptible organisms, including fungi
- Cross-allergenicity among aminoglycosides has been demonstrated
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (141)
- Cidofovir + Tobramycin Contraindicated
- Adefovir + Tobramycin Major
- Amikacin + Tobramycin Major
- Amphotericin b + Tobramycin Major
- Amphotericin b deoxycholate + Tobramycin Major
- Atracurium + Tobramycin Major
- Bacitracin + Tobramycin Major
- Bumetanide + Tobramycin Major
- Capreomycin + Tobramycin Major
- Cephaloridine + Tobramycin Major
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Tobramycin 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Tobramycin used for?
Tobramycin is a medicine in the class anti bacterial. It is used for Bacterial infections, Conjunctivitis, Cystic fibrosis.
What side effects have been reported with Tobramycin?
Neurotoxicity, Increased lacrimation, Nephrotoxicity, Itching and edema of eyelid, Ototoxicity.
Can Tobramycin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Injection: aminoglycosides can cause fetal harm; streptomycin has caused permanent congenital deafness. Use only for serious infections with drug-level monitoring. Inhaled form gives minimal absorption. Eye/ear drops: little absorbed; acceptable. Breastfeeding: Safe. Poorly excreted into milk; infant blood levels are far below treatment levels. LactMed: acceptable; watch for diarrhoea, thrush or nappy rash. Inhaled tobramycin is compatible (respiratory experts); eye or ear drops pose little or no risk.
What does Tobramycin interact with?
MediHelp lists 141 known interactions for Tobramycin. Contraindicated: 1 · Major: 41 · Moderate: 75 · Minor: 24. The most serious include Cidofovir, Adefovir, Amikacin.
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