藥物交互作用
Cidofovir + Tobramycin
嚴重程度: 禁忌併用
Cidofovir and Tobramycin: contraindicated interaction.
最後更新
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摘要
Both agents are toxic to the renal tubule, so together they can cause serious acute kidney injury. Cidofovir labeling contraindicates its use with other nephrotoxic drugs such as aminoglycosides.
用白話說明這項交互作用的意義
Cidofovir and Tobramycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cidofovir belongs to Anti Virals; Tobramycin belongs to Anti Bacterial.
為什麼會發生
Additive direct tubular nephrotoxicity.
處置方式
Do not co-administer; stop tobramycin at least 7 days before cidofovir or select a non-nephrotoxic alternative.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Tobramycin 的其他交互作用
Cidofovir 的其他交互作用
常見問題
Can I take Cidofovir with Tobramycin?
MediHelp rates the interaction as contraindicated. Cidofovir and Tobramycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are toxic to the renal tubule, so together they can cause serious acute kidney injury. Cidofovir labeling contraindicates its use with other nephrotoxic drugs such as aminoglycosides.
How serious is the interaction between Cidofovir and Tobramycin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; stop tobramycin at least 7 days before cidofovir or select a non-nephrotoxic alternative.
What other medicines interact with Tobramycin?
MediHelp also lists interactions of Tobramycin with, for example, Adefovir, Amikacin, Amphotericin b deoxycholate. The full list is on the Tobramycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
