藥物交互作用
Trientine + Zinc
嚴重程度: 中度
Trientine and Zinc: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Zinc supplements can reduce trientine absorption and also bind it, which may weaken copper chelation in Wilson disease.
用白話說明這項交互作用的意義
Trientine and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Trientine belongs to Miscellaneous; Zinc belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of trientine by zinc ions in the gut reduces its absorption.
處置方式
Avoid concurrent use; if needed, take trientine at least 1 hour before or 2 hours after zinc. Monitor copper indices.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Trientine 的其他交互作用
Zinc 的其他交互作用
常見問題
Can I take Trientine with Zinc?
MediHelp rates the interaction as moderate. Trientine and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc supplements can reduce trientine absorption and also bind it, which may weaken copper chelation in Wilson disease.
How serious is the interaction between Trientine and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; if needed, take trientine at least 1 hour before or 2 hours after zinc. Monitor copper indices.
What other medicines interact with Trientine?
MediHelp also lists interactions of Trientine with, for example, Calcium, Carbonyl iron, Copper. The full list is on the Trientine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
