藥物交互作用
Acalabrutinib + Eptifibatide
嚴重程度: 嚴重
Acalabrutinib and Eptifibatide: major interaction.
最後更新
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摘要
Acalabrutinib impairs platelet function through BTK inhibition and is associated with bruising and hemorrhage. Adding eptifibatide, a glycoprotein IIb/IIIa inhibitor, increases the likelihood of significant bleeding.
用白話說明這項交互作用的意義
Acalabrutinib and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acalabrutinib belongs to Oncology; Eptifibatide belongs to Cardiovascular.
為什麼會發生
Additive impairment of platelet function via BTK inhibition and glycoprotein IIb/IIIa receptor blockade.
處置方式
Avoid combining where possible; if eptifibatide is essential, monitor closely for bleeding and hemoglobin. Consider holding acalabrutinib around invasive procedures.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Eptifibatide 的其他交互作用
Acalabrutinib 的其他交互作用
常見問題
Can I take Acalabrutinib with Eptifibatide?
MediHelp rates the interaction as major. Acalabrutinib and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Acalabrutinib impairs platelet function through BTK inhibition and is associated with bruising and hemorrhage. Adding eptifibatide, a glycoprotein IIb/IIIa inhibitor, increases the likelihood of significant bleeding.
How serious is the interaction between Acalabrutinib and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; if eptifibatide is essential, monitor closely for bleeding and hemoglobin. Consider holding acalabrutinib around invasive procedures.
What other medicines interact with Eptifibatide?
MediHelp also lists interactions of Eptifibatide with, for example, Abrocitinib, Acetylsalicylic acid, Antithrombin alfa. The full list is on the Eptifibatide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
