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Eptifibatide

Eptifibatide is a medicine in the class cardiovascular. It is used for acute coronary syndrome.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Cardiovascular
ATC 代碼
B01AC16
常見劑型
注射劑
常見規格
0.75 mg/ml, 2 mg/ml
已知交互作用
42 (嚴重: 21 · 中度: 10 · 輕微: 11)
商品名
3
國家與市場
2

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Blocks binding of fibrinogen and von Willebrand factor to glycoprotein IIb/IIIa receptor on platelet surface

成人常用劑量（仿單摘要）

Acute Coronary Syndromes: 180 mcg/kg IV bolus over 1-2 min, THEN 2 mcg/kg/min IV continuous infusion; continue infusion until hospital discharge or initiation of coronary artery bypass graft surgery (CABG), up to 72 hours

僅摘錄仿單中第一行劑量說明；完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Published reports are too few to assess risk; untreated heart attack can be fatal to mother and fetus. Bleeding is the main risk, especially near delivery. EU label: do not use unless clearly necessary.
哺乳
Unknown No milk data. A peptide likely destroyed in the infant gut. EU label: interrupt breastfeeding during treatment. LactMed: use with caution and watch the infant for bruising or bleeding. Given as a short IV course.

已通報的副作用

  • Injection site reaction
  • Thrombocytopenia
  • Hypotension
  • Bleeding

禁忌症

  • History of internal bleeding, intracranial hemorrhage or neoplasm, CVA, thrombocytopenia
  • AV malformation or aneurysm, aortic dissection, severe HTN, acute pericarditis
  • Other parenteral glycoprotein IIb/IIIa inhibitors

哪些人需要特別留意

  • In patients undergoing PCI, treatment may increase in major and minor bleeding at site of arterial sheath placement

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。

重要交互作用 (42)

All 42 interactions, with severity and what to do

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  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Dosing in older adults
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
  • IV preparation and dilution
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同類別的其他藥品

常見問題

What is Eptifibatide used for?

Eptifibatide is a medicine in the class cardiovascular. It is used for Acute coronary syndrome, Percutaneous coronary intervention.

What side effects have been reported with Eptifibatide?

Injection site reaction, Thrombocytopenia, Hypotension, Bleeding.

Can Eptifibatide be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Published reports are too few to assess risk; untreated heart attack can be fatal to mother and fetus. Bleeding is the main risk, especially near delivery. EU label: do not use unless clearly necessary. Breastfeeding: Unknown. No milk data. A peptide likely destroyed in the infant gut. EU label: interrupt breastfeeding during treatment. LactMed: use with caution and watch the infant for bruising or bleeding. Given as a short IV course.

What does Eptifibatide interact with?

MediHelp lists 42 known interactions for Eptifibatide. Major: 21 · Moderate: 10 · Minor: 11. The most serious include Abrocitinib, Acalabrutinib, Acetylsalicylic acid.

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