藥物交互作用
Apixaban + Eptifibatide
嚴重程度: 嚴重
Apixaban and Eptifibatide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.
用白話說明這項交互作用的意義
Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Apixaban belongs to Cardiovascular; Eptifibatide belongs to Cardiovascular.
為什麼會發生
Additive hemostatic impairment from platelet aggregation blockade and factor Xa inhibition.
處置方式
Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Apixaban 的其他交互作用
Eptifibatide 的其他交互作用
常見問題
Can I take Apixaban with Eptifibatide?
MediHelp rates the interaction as major. Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.
How serious is the interaction between Apixaban and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
