藥物交互作用
Aceclofenac + Sulphasalazine
嚴重程度: 中度
Aceclofenac and Sulphasalazine: moderate interaction.
最後更新
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摘要
Aceclofenac is an NSAID and sulfasalazine contains a salicylate-related moiety, so combined use may add to gastrointestinal irritation, renal effects and bleeding tendency. Clinically significant harm is uncommon but possible in at-risk patients.
用白話說明這項交互作用的意義
Aceclofenac and Sulphasalazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aceclofenac belongs to Musculoskeletal; Sulphasalazine belongs to Gastrointestinal Tract.
為什麼會發生
Additive NSAID effects on platelet function, gastric mucosa and renal prostaglandins.
處置方式
Use the lowest effective NSAID dose and monitor for gastrointestinal bleeding, renal function and blood counts. Consider gastroprotection in high-risk patients.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Sulphasalazine 的其他交互作用
Aceclofenac 的其他交互作用
常見問題
Can I take Aceclofenac with Sulphasalazine?
MediHelp rates the interaction as moderate. Aceclofenac and Sulphasalazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aceclofenac is an NSAID and sulfasalazine contains a salicylate-related moiety, so combined use may add to gastrointestinal irritation, renal effects and bleeding tendency. Clinically significant harm is uncommon but possible in at-risk patients.
How serious is the interaction between Aceclofenac and Sulphasalazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective NSAID dose and monitor for gastrointestinal bleeding, renal function and blood counts. Consider gastroprotection in high-risk patients.
What other medicines interact with Sulphasalazine?
MediHelp also lists interactions of Sulphasalazine with, for example, Deferiprone, Pexidartinib, Sepiapterin. The full list is on the Sulphasalazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
