藥物交互作用
Deferiprone + Sulphasalazine
嚴重程度: 嚴重
Deferiprone and Sulphasalazine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both drugs can cause neutropenia and agranulocytosis. Combined use raises the risk of serious infection from bone marrow suppression.
用白話說明這項交互作用的意義
Deferiprone and Sulphasalazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Sulphasalazine belongs to Gastrointestinal Tract.
為什麼會發生
Additive myelosuppressive toxicity affecting neutrophils.
處置方式
Avoid combining where an alternative exists. If unavoidable, check absolute neutrophil counts more frequently and stop therapy promptly if neutropenia develops.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Sulphasalazine 的其他交互作用
Deferiprone 的其他交互作用
常見問題
Can I take Deferiprone with Sulphasalazine?
MediHelp rates the interaction as major. Deferiprone and Sulphasalazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can cause neutropenia and agranulocytosis. Combined use raises the risk of serious infection from bone marrow suppression.
How serious is the interaction between Deferiprone and Sulphasalazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where an alternative exists. If unavoidable, check absolute neutrophil counts more frequently and stop therapy promptly if neutropenia develops.
What other medicines interact with Sulphasalazine?
MediHelp also lists interactions of Sulphasalazine with, for example, Pexidartinib, Sepiapterin, Acalabrutinib. The full list is on the Sulphasalazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
