藥物交互作用
Adenovirus types 4 and 7 live + Etoposide
嚴重程度: 禁忌併用
Adenovirus types 4 and 7 live and Etoposide: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Etoposide causes immunosuppression, so a live adenovirus vaccine may cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
用白話說明這項交互作用的意義
Adenovirus types 4 and 7 live and Etoposide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Chemotherapy-induced immunosuppression impairs control of live attenuated virus and reduces vaccine immunogenicity.
處置方式
Do not give the live vaccine during etoposide therapy; wait at least 3 months after chemotherapy ends and until immune recovery.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Etoposide 的其他交互作用
常見問題
Can I take Adenovirus types 4 and 7 live with Etoposide?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Etoposide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Etoposide causes immunosuppression, so a live adenovirus vaccine may cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
How serious is the interaction between Adenovirus types 4 and 7 live and Etoposide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during etoposide therapy; wait at least 3 months after chemotherapy ends and until immune recovery.
What other medicines interact with Etoposide?
MediHelp also lists interactions of Etoposide with, for example, Pentostatin, Cyclosporine, Cyclosporin. The full list is on the Etoposide page.
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