藥品參考
Etoposide
Etoposide is a medicine in the class oncology. It is used for lung cancer.
- 藥物類別: Oncology
- 用途: lung cancer
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重點資訊
- 藥物類別
- Oncology
- 常見劑型
- 注射劑, 膠囊, 輸注液
- 常見規格
- 100 mg/5 ml, 100 mg, 50 mg
- 已知交互作用
- 130 (禁忌併用: 2 · 嚴重: 10 · 中度: 99 · 輕微: 19)
- 商品名
- 19
- 國家與市場
- 4
用途
作用方式
Appears to inhibit or alter DNA replication, induces G2-phase arrest & preferentially kills cells in G2 & late S phases
成人常用劑量（仿單摘要）
Testicular Cancer: 50-100 mg/m²/day IV on days 1-5, OR 100 mg/m²/day IV on days 1, 3, 5 Repeat q3-4week
懷孕與哺乳
- 懷孕
- Unsafe Can cause fetal harm: in animals it caused embryo death and malformations at doses below human doses; it acts on dividing cells. Avoid in pregnancy. Use effective contraception during treatment and for 6 months after the last dose (Avopef label).
- 哺乳
- Unsafe Passes into milk. Most sources say do not breastfeed during chemotherapy. LactMed: with intermittent courses, breastfeeding might resume after a break (at least 24 to 72 hours after a dose); discuss with the oncology team.
已通報的副作用
- Vomiting
- Diarrhea
- Nausea
- Anorexia
- Leukopenia
- Alopecia
哪些人需要特別留意
- Prescriber must consider benefits versus risk of therapy; if severe reactions occur, dose should be reduced or discontinued and appropriate corrective measures taken
- Patients with low serum albumin may be at increased risk for etoposide associated toxicities
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (130)
- Adenovirus types 4 and 7 live + Etoposide Contraindicated
- Etoposide + Pentostatin Contraindicated
- Cyclosporin + Etoposide Major
- Cyclosporine + Etoposide Major
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Etoposide Major
- Etoposide + Fingolimod Major
- Etoposide + Fosphenytoin Major
- Etoposide + Idelalisib Major
- Etoposide + Levoketoconazole Major
- Etoposide + Olaparib Major
同類別的其他藥品
常見問題
What is Etoposide used for?
Etoposide is a medicine in the class oncology. It is used for Lung cancer, Testicular cancer.
What side effects have been reported with Etoposide?
Vomiting, Diarrhea, Nausea, Anorexia, Leukopenia, Alopecia.
Can Etoposide be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Can cause fetal harm: in animals it caused embryo death and malformations at doses below human doses; it acts on dividing cells. Avoid in pregnancy. Use effective contraception during treatment and for 6 months after the last dose (Avopef label). Breastfeeding: Unsafe. Passes into milk. Most sources say do not breastfeed during chemotherapy. LactMed: with intermittent courses, breastfeeding might resume after a break (at least 24 to 72 hours after a dose); discuss with the oncology team.
What does Etoposide interact with?
MediHelp lists 130 known interactions for Etoposide. Contraindicated: 2 · Major: 10 · Moderate: 99 · Minor: 19. The most serious include Adenovirus types 4 and 7 live, Pentostatin, Cyclosporin.
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