藥物交互作用
Adenovirus types 4 and 7 live + Mitoxantrone
嚴重程度: 禁忌併用
Adenovirus types 4 and 7 live and Mitoxantrone: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Mitoxantrone causes myelosuppression and immunosuppression. A live oral adenovirus vaccine could cause disseminated vaccine-virus infection, and the immune response to it will be poor.
用白話說明這項交互作用的意義
Adenovirus types 4 and 7 live and Mitoxantrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Immunosuppression impairs control of live attenuated virus replication and reduces vaccine immunogenicity.
處置方式
Do not give live vaccines during mitoxantrone therapy. Wait at least 3 months after stopping and confirm immune recovery before vaccinating.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Mitoxantrone 的其他交互作用
常見問題
Can I take Adenovirus types 4 and 7 live with Mitoxantrone?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Mitoxantrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mitoxantrone causes myelosuppression and immunosuppression. A live oral adenovirus vaccine could cause disseminated vaccine-virus infection, and the immune response to it will be poor.
How serious is the interaction between Adenovirus types 4 and 7 live and Mitoxantrone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during mitoxantrone therapy. Wait at least 3 months after stopping and confirm immune recovery before vaccinating.
What other medicines interact with Mitoxantrone?
MediHelp also lists interactions of Mitoxantrone with, for example, Axicabtagene ciloleucel, Belatacept, Brexucabtagene autoleucel. The full list is on the Mitoxantrone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
