藥物交互作用
Alfentanil + Fentanyl
嚴重程度: 嚴重
Alfentanil and Fentanyl: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Combining fentanyl and alfentanil, both potent opioids, produces additive sedation, respiratory depression and hypotension. In supervised anesthesia this is often intended, but outside it risks overdose.
用白話說明這項交互作用的意義
Alfentanil and Fentanyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive mu-opioid receptor agonism.
處置方式
Avoid concurrent use outside monitored anesthesia settings; if both are given, reduce doses and monitor ventilation and sedation.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fentanyl 的其他交互作用
常見問題
Can I take Alfentanil with Fentanyl?
MediHelp rates the interaction as major. Alfentanil and Fentanyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining fentanyl and alfentanil, both potent opioids, produces additive sedation, respiratory depression and hypotension. In supervised anesthesia this is often intended, but outside it risks overdose.
How serious is the interaction between Alfentanil and Fentanyl?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use outside monitored anesthesia settings; if both are given, reduce doses and monitor ventilation and sedation.
What other medicines interact with Fentanyl?
MediHelp also lists interactions of Fentanyl with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Fentanyl page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
