藥物交互作用
Alogliptin-metformin + Mecasermin
嚴重程度: 中度
Alogliptin-metformin and Mecasermin: moderate interaction.
最後更新
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摘要
Mecasermin is recombinant IGF-1 and can cause significant hypoglycemia. Added to antidiabetic drugs, it may increase the risk of low blood glucose, although metformin and alogliptin carry little hypoglycemia risk alone.
用白話說明這項交互作用的意義
Alogliptin-metformin and Mecasermin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Mecasermin belongs to Endocrine.
為什麼會發生
IGF-1 has insulin-like glucose-lowering activity that adds to the effects of antidiabetic drugs.
處置方式
Give mecasermin with or shortly after a meal and monitor blood glucose frequently. Educate the patient about hypoglycemia symptoms and adjust antidiabetic doses as required.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alogliptin-metformin 的其他交互作用
Mecasermin 的其他交互作用
常見問題
Can I take Alogliptin-metformin with Mecasermin?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Mecasermin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mecasermin is recombinant IGF-1 and can cause significant hypoglycemia. Added to antidiabetic drugs, it may increase the risk of low blood glucose, although metformin and alogliptin carry little hypoglycemia risk alone.
How serious is the interaction between Alogliptin-metformin and Mecasermin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give mecasermin with or shortly after a meal and monitor blood glucose frequently. Educate the patient about hypoglycemia symptoms and adjust antidiabetic doses as required.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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