藥物交互作用
Insulin neutral human + Mecasermin
嚴重程度: 嚴重
Insulin neutral human and Mecasermin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Mecasermin is recombinant IGF-1 and has insulin-like glucose-lowering effects, so combining with insulin can cause additive and sometimes severe hypoglycemia. Mecasermin labeling warns of hypoglycemia, particularly without food.
用白話說明這項交互作用的意義
Insulin neutral human and Mecasermin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin neutral human belongs to Endocrine; Mecasermin belongs to Endocrine.
為什麼會發生
IGF-1 receptor activation, with some insulin receptor activity, adds to insulin's glucose-lowering effect.
處置方式
Give mecasermin with or shortly after a meal and monitor glucose closely, reducing the insulin dose as needed. Ensure the patient and caregivers know how to treat hypoglycemia.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin neutral human 的其他交互作用
Mecasermin 的其他交互作用
常見問題
Can I take Insulin neutral human with Mecasermin?
MediHelp rates the interaction as major. Insulin neutral human and Mecasermin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Mecasermin is recombinant IGF-1 and has insulin-like glucose-lowering effects, so combining with insulin can cause additive and sometimes severe hypoglycemia. Mecasermin labeling warns of hypoglycemia, particularly without food.
How serious is the interaction between Insulin neutral human and Mecasermin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give mecasermin with or shortly after a meal and monitor glucose closely, reducing the insulin dose as needed. Ensure the patient and caregivers know how to treat hypoglycemia.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Pentamidine. The full list is on the Insulin neutral human page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
