藥品參考
Mecasermin
Mecasermin is a medicine in the class endocrine. It is used for growth failure.
- 藥物類別: Endocrine
- 用途: growth failure
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Endocrine
- ATC 代碼
- H01AC03
- 常見劑型
- 注射劑
- 常見規格
- 10 mg/ml, 40 mg, 40 mg/4 ml
- 已知交互作用
- 46 (嚴重: 6 · 中度: 37 · 輕微: 3)
- 商品名
- 3
- 國家與市場
- 3
用途
作用方式
Recombinant human IGF-1 used as replacement therapy in patients primary severe IGF-I deficiency, growth hormone receptors in the liver that are unresponsive to GH
成人常用劑量（仿單摘要）
Not indicated for adult use
懷孕與哺乳
- 懷孕
- Unknown Used in children with IGF-1 deficiency; exposure in pregnancy is unlikely as it is not used after growth plates close. No human data; no birth defects in rats or rabbits, but fetal deaths in rabbits above the human dose. Use only if clearly needed.
- 哺乳
- Unknown No data on passage into milk or effects on the infant. It is a protein, so little would be absorbed by the infant; it contains benzyl alcohol. US label: weigh breastfeeding benefits against the mother's need.
已通報的副作用
- Dizziness
- Convulsion
- Hypoglycemia
- Tonsillar hypertrophy
- Cardiac murmur
哪些人需要特別留意
- Allergic reactions reported include localized (injection site) reactions to severe systemic reactions, including anaphylaxis requiring hospitalization
- Symptoms associated with intracranial hypertension including nausea, headache, papilledema, vomiting, visual changes reported; funduscopic examinations are recommended
- Lymphoid hypertrophy that may lead to complications such as chronic middle ear effusions, snoring, and sleep apnea reported
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (46)
- Gliclazide + Mecasermin Major
- Glyburide-metformin + Mecasermin Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-liraglutide + Mecasermin Major
- Insulin glargine-lixisenatide + Mecasermin Major
- Insulin neutral human + Mecasermin Major
- Acarbose + Mecasermin Moderate
- Alogliptin-metformin + Mecasermin Moderate
- Alogliptin-pioglitazone + Mecasermin Moderate
- Canagliflozin-metformin + Mecasermin Moderate
同類別的其他藥品
常見問題
What is Mecasermin used for?
Mecasermin is a medicine in the class endocrine. It is used for Growth failure.
What side effects have been reported with Mecasermin?
Dizziness, Convulsion, Hypoglycemia, Tonsillar hypertrophy, Cardiac murmur.
Can Mecasermin be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Used in children with IGF-1 deficiency; exposure in pregnancy is unlikely as it is not used after growth plates close. No human data; no birth defects in rats or rabbits, but fetal deaths in rabbits above the human dose. Use only if clearly needed. Breastfeeding: Unknown. No data on passage into milk or effects on the infant. It is a protein, so little would be absorbed by the infant; it contains benzyl alcohol. US label: weigh breastfeeding benefits against the mother's need.
What does Mecasermin interact with?
MediHelp lists 46 known interactions for Mecasermin. Major: 6 · Moderate: 37 · Minor: 3. The most serious include Gliclazide, Glyburide-metformin, Insulin degludec-insulin aspart.
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