藥物交互作用
Alogliptin-metformin + Somatropin
嚴重程度: 中度
Alogliptin-metformin and Somatropin: moderate interaction.
最後更新
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摘要
Somatropin can reduce insulin sensitivity and raise blood glucose, which may weaken the effect of antidiabetic drugs. Patients with diabetes may need dose increases after growth hormone is started.
用白話說明這項交互作用的意義
Alogliptin-metformin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Somatropin belongs to Endocrine.
為什麼會發生
Growth hormone induces insulin resistance and increases hepatic glucose output, opposing glucose-lowering drugs.
處置方式
Monitor blood glucose when somatropin is started or its dose changed, and adjust antidiabetic therapy accordingly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alogliptin-metformin 的其他交互作用
Somatropin 的其他交互作用
常見問題
Can I take Alogliptin-metformin with Somatropin?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatropin can reduce insulin sensitivity and raise blood glucose, which may weaken the effect of antidiabetic drugs. Patients with diabetes may need dose increases after growth hormone is started.
How serious is the interaction between Alogliptin-metformin and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when somatropin is started or its dose changed, and adjust antidiabetic therapy accordingly.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
