藥物交互作用
Betamethasone + Somatropin
嚴重程度: 中度
Betamethasone and Somatropin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Supraphysiologic glucocorticoid doses can blunt the growth-promoting effect of somatropin, which matters most in children. Growth hormone also reduces cortisol regeneration, so glucocorticoid replacement needs may change.
用白話說明這項交互作用的意義
Betamethasone and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betamethasone belongs to Endocrine; Somatropin belongs to Endocrine.
為什麼會發生
Glucocorticoids antagonize growth hormone action, and growth hormone inhibits 11-beta-HSD-1, which alters cortisol activation.
處置方式
Use the lowest effective glucocorticoid dose and track growth velocity in children. Reassess glucocorticoid dosing in hypopituitary patients after starting somatropin.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Somatropin 的其他交互作用
Betamethasone 的其他交互作用
常見問題
Can I take Betamethasone with Somatropin?
MediHelp rates the interaction as moderate. Betamethasone and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Supraphysiologic glucocorticoid doses can blunt the growth-promoting effect of somatropin, which matters most in children. Growth hormone also reduces cortisol regeneration, so glucocorticoid replacement needs may change.
How serious is the interaction between Betamethasone and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective glucocorticoid dose and track growth velocity in children. Reassess glucocorticoid dosing in hypopituitary patients after starting somatropin.
What other medicines interact with Somatropin?
MediHelp also lists interactions of Somatropin with, for example, Acarbose, Albiglutide, Alogliptin-metformin. The full list is on the Somatropin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
