藥物交互作用
Alogliptin + Somatropin
嚴重程度: 中度
Alogliptin and Somatropin: moderate interaction.
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摘要
Growth hormone reduces insulin sensitivity and can raise blood glucose, which may offset the glucose-lowering effect of alogliptin. Glycemic control may deteriorate after somatropin is started or the dose increased.
用白話說明這項交互作用的意義
Alogliptin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin belongs to Endocrine; Somatropin belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism: growth hormone induces insulin resistance and raises hepatic glucose output.
處置方式
Monitor fasting glucose and HbA1c when starting or adjusting somatropin. Adjust the antidiabetic regimen as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Somatropin 的其他交互作用
Alogliptin 的其他交互作用
常見問題
Can I take Alogliptin with Somatropin?
MediHelp rates the interaction as moderate. Alogliptin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone reduces insulin sensitivity and can raise blood glucose, which may offset the glucose-lowering effect of alogliptin. Glycemic control may deteriorate after somatropin is started or the dose increased.
How serious is the interaction between Alogliptin and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor fasting glucose and HbA1c when starting or adjusting somatropin. Adjust the antidiabetic regimen as needed.
What other medicines interact with Somatropin?
MediHelp also lists interactions of Somatropin with, for example, Acarbose, Albiglutide, Alogliptin-metformin. The full list is on the Somatropin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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