藥物交互作用
Alogliptin-pioglitazone + Somapacitan
嚴重程度: 中度
Alogliptin-pioglitazone and Somapacitan: moderate interaction.
最後更新
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摘要
Growth hormone analogs can reduce insulin sensitivity and raise blood glucose, working against the effect of antidiabetic drugs. Glycemic control may worsen, especially at higher doses or in patients with diabetes.
用白話說明這項交互作用的意義
Alogliptin-pioglitazone and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Somapacitan belongs to Endocrine.
為什麼會發生
Growth hormone induces insulin resistance, opposing the glucose-lowering effect of pioglitazone and alogliptin.
處置方式
Monitor blood glucose and HbA1c after starting somapacitan and increase antidiabetic therapy as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alogliptin-pioglitazone 的其他交互作用
Somapacitan 的其他交互作用
常見問題
Can I take Alogliptin-pioglitazone with Somapacitan?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone analogs can reduce insulin sensitivity and raise blood glucose, working against the effect of antidiabetic drugs. Glycemic control may worsen, especially at higher doses or in patients with diabetes.
How serious is the interaction between Alogliptin-pioglitazone and Somapacitan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting somapacitan and increase antidiabetic therapy as needed.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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