藥物交互作用
Cyclosporin + Somapacitan
嚴重程度: 中度
Cyclosporin and Somapacitan: moderate interaction.
最後更新
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摘要
Growth hormone may increase CYP450-mediated drug clearance. Cyclosporine exposure could fall, risking loss of immunosuppression and rejection or graft-versus-host disease.
用白話說明這項交互作用的意義
Cyclosporin and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclosporin belongs to Miscellaneous; Somapacitan belongs to Endocrine.
為什麼會發生
Growth hormone may induce CYP3A4 activity, increasing cyclosporine metabolism; evidence is limited.
處置方式
Monitor cyclosporine trough concentrations after starting or changing somapacitan. Increase the cyclosporine dose if levels fall below target.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cyclosporin 的其他交互作用
Somapacitan 的其他交互作用
常見問題
Can I take Cyclosporin with Somapacitan?
MediHelp rates the interaction as moderate. Cyclosporin and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone may increase CYP450-mediated drug clearance. Cyclosporine exposure could fall, risking loss of immunosuppression and rejection or graft-versus-host disease.
How serious is the interaction between Cyclosporin and Somapacitan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor cyclosporine trough concentrations after starting or changing somapacitan. Increase the cyclosporine dose if levels fall below target.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
