藥物交互作用
Chlorpropamide + Somapacitan
嚴重程度: 中度
Chlorpropamide and Somapacitan: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Growth hormone analogs can reduce insulin sensitivity and raise blood glucose. In a patient taking chlorpropamide, glycemic control may deteriorate after somapacitan is started or the dose is increased.
用白話說明這項交互作用的意義
Chlorpropamide and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpropamide belongs to Endocrine; Somapacitan belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism: growth hormone induces insulin resistance, opposing the glucose-lowering effect of the sulfonylurea.
處置方式
Monitor blood glucose and HbA1c after starting or adjusting somapacitan. Increase the antidiabetic dose or add therapy if glycemic control worsens.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chlorpropamide 的其他交互作用
Somapacitan 的其他交互作用
常見問題
Can I take Chlorpropamide with Somapacitan?
MediHelp rates the interaction as moderate. Chlorpropamide and Somapacitan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone analogs can reduce insulin sensitivity and raise blood glucose. In a patient taking chlorpropamide, glycemic control may deteriorate after somapacitan is started or the dose is increased.
How serious is the interaction between Chlorpropamide and Somapacitan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting or adjusting somapacitan. Increase the antidiabetic dose or add therapy if glycemic control worsens.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
