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藥物交互作用

Alprazolam + Lasmiditan

嚴重程度: 中度

Alprazolam and Lasmiditan: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.

用白話說明這項交互作用的意義

Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Alprazolam belongs to Central Nervous System; Lasmiditan belongs to Central Nervous System.

證據等級: Low

為什麼會發生

Additive central nervous system depression through pharmacodynamic synergism.

處置方式

Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Alprazolam 與 Lasmiditan 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Alprazolam with Lasmiditan?

MediHelp rates the interaction as moderate. Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.

How serious is the interaction between Alprazolam and Lasmiditan?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.

What other medicines interact with Alprazolam?

MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.

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