藥物交互作用
Amiodarone + Lasmiditan
嚴重程度: 中度
Amiodarone and Lasmiditan: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Lasmiditan inhibits P-glycoprotein in vitro and may raise exposure to P-gp substrates such as amiodarone. The clinical significance is uncertain.
用白話說明這項交互作用的意義
Amiodarone and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amiodarone belongs to Cardiovascular; Lasmiditan belongs to Central Nervous System.
為什麼會發生
Lasmiditan inhibits P-glycoprotein efflux, potentially raising amiodarone levels.
處置方式
Monitor heart rate and ECG, and watch for amiodarone adverse effects.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amiodarone 的其他交互作用
Lasmiditan 的其他交互作用
常見問題
Can I take Amiodarone with Lasmiditan?
MediHelp rates the interaction as moderate. Amiodarone and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan inhibits P-glycoprotein in vitro and may raise exposure to P-gp substrates such as amiodarone. The clinical significance is uncertain.
How serious is the interaction between Amiodarone and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and ECG, and watch for amiodarone adverse effects.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
