藥品參考
Lasmiditan
Lasmiditan is a medicine in the class central nervous system. It is used for migraine.
- 藥物類別: Central Nervous System
- 用途: migraine
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Central Nervous System
- ATC 代碼
- N02CC08
- 常見劑型
- 錠劑
- 常見規格
- 100 mg
- 已知交互作用
- 220 (中度: 159 · 輕微: 61)
- 商品名
- 3
- 國家與市場
- 3
用途
作用方式
Binds with high affinity to the 5-HT1F receptor and presumably acts through agonist effects at this receptor; the precise mechanism is unknown.
成人常用劑量（仿單摘要）
Acute treatment of migraine with or without aura: 50 mg, 100 mg, or 200 mg orally as needed; no more than one dose in 24 hours
懷孕與哺乳
- 懷孕
- Unsafe No adequate human data. In animals it caused fetal abnormalities, fetal and pup deaths and lower fetal weight, in rabbits at exposures below human levels. EU label: not recommended in pregnancy. Prefer a better-studied migraine drug (e.g. sumatriptan); a pregnancy registry exists.
- 哺乳
- Unknown No human milk data; rat milk levels were about 3 times plasma. US label: weigh benefits. EU label: decide; avoiding breastfeeding for 24 hours after a dose minimises exposure. LactMed: not a reason to stop for an older infant, but another drug may be preferred for a newborn or preterm infant.
已通報的副作用
- Dizziness
- Fatigue
- Paresthesia
- Sedation
- Nausea and/or vomiting
- Muscle weakness
哪些人需要特別留意
- Driving impairment: do not drive or operate machinery for at least 8 hours after each dose; patients unable to comply should not take it.
- CNS depression, including dizziness and sedation; use caution with alcohol or other CNS depressants.
- Serotonin syndrome reported; discontinue if suspected.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (220)
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
- Atenolol + Lasmiditan Moderate
- Atenolol-chlorthalidone + Lasmiditan Moderate
- Atorvastatin + Lasmiditan Moderate
- Baclofen + Lasmiditan Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Lasmiditan 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Lasmiditan used for?
Lasmiditan is a medicine in the class central nervous system. It is used for Migraine.
What side effects have been reported with Lasmiditan?
Dizziness, Fatigue, Paresthesia, Sedation, Nausea and/or vomiting, Muscle weakness.
Can Lasmiditan be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. No adequate human data. In animals it caused fetal abnormalities, fetal and pup deaths and lower fetal weight, in rabbits at exposures below human levels. EU label: not recommended in pregnancy. Prefer a better-studied migraine drug (e.g. sumatriptan); a pregnancy registry exists. Breastfeeding: Unknown. No human milk data; rat milk levels were about 3 times plasma. US label: weigh benefits. EU label: decide; avoiding breastfeeding for 24 hours after a dose minimises exposure. LactMed: not a reason to stop for an older infant, but another drug may be preferred for a newborn or preterm infant.
What does Lasmiditan interact with?
MediHelp lists 220 known interactions for Lasmiditan. Moderate: 159 · Minor: 61. The most serious include Alprazolam, Amiodarone, Amisulpride.
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