藥物交互作用
Aluminum hydroxide + Etidronate
嚴重程度: 中度
Aluminum hydroxide and Etidronate: moderate interaction.
最後更新
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摘要
Divalent and trivalent cations in antacids bind etidronate and markedly reduce its oral absorption. This can compromise efficacy for bone disease.
用白話說明這項交互作用的意義
Aluminum hydroxide and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Etidronate belongs to Musculoskeletal.
為什麼會發生
Aluminum forms insoluble chelate complexes with etidronate in the gut, reducing absorption.
處置方式
Take etidronate on an empty stomach and avoid antacids for at least 2 hours before and after the dose.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aluminum hydroxide 的其他交互作用
Etidronate 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Etidronate?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Divalent and trivalent cations in antacids bind etidronate and markedly reduce its oral absorption. This can compromise efficacy for bone disease.
How serious is the interaction between Aluminum hydroxide and Etidronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take etidronate on an empty stomach and avoid antacids for at least 2 hours before and after the dose.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。