藥物交互作用
Aluminum hydroxide / magnesium trisilicate + Ethambutol
嚴重程度: 中度
Aluminum hydroxide / magnesium trisilicate and Ethambutol: moderate interaction.
最後更新
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摘要
Aluminium-containing antacids can reduce ethambutol absorption, which may lower its blood levels and weaken antimycobacterial effect. The effect is predicted rather than firmly established.
用白話說明這項交互作用的意義
Aluminum hydroxide / magnesium trisilicate and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Aluminium and magnesium cations may bind ethambutol in the gut or alter gastric conditions, reducing absorption.
處置方式
Give ethambutol at least 4 hours before aluminium-containing antacids. Monitor treatment response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ethambutol 的其他交互作用
常見問題
Can I take Aluminum hydroxide / magnesium trisilicate with Ethambutol?
MediHelp rates the interaction as moderate. Aluminum hydroxide / magnesium trisilicate and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium-containing antacids can reduce ethambutol absorption, which may lower its blood levels and weaken antimycobacterial effect. The effect is predicted rather than firmly established.
How serious is the interaction between Aluminum hydroxide / magnesium trisilicate and Ethambutol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ethambutol at least 4 hours before aluminium-containing antacids. Monitor treatment response.
What other medicines interact with Ethambutol?
MediHelp also lists interactions of Ethambutol with, for example, Allopurinol, Aluminum hydroxide / magnesium carbonate, Bcg vaccine live. The full list is on the Ethambutol page.
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