藥物交互作用
Amikacin + Cefiderocol
嚴重程度: 中度
Amikacin and Cefiderocol: moderate interaction.
最後更新
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摘要
Amikacin can cause kidney injury and ototoxicity, and giving it with a cephalosporin may modestly add to renal risk. Cefiderocol is renally eliminated, so reduced renal function increases its exposure.
用白話說明這項交互作用的意義
Amikacin and Cefiderocol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefiderocol belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity, not firmly established for cefiderocol.
處置方式
Monitor renal function and amikacin trough concentrations, and adjust doses to creatinine clearance.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amikacin 的其他交互作用
Cefiderocol 的其他交互作用
常見問題
Can I take Amikacin with Cefiderocol?
MediHelp rates the interaction as moderate. Amikacin and Cefiderocol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amikacin can cause kidney injury and ototoxicity, and giving it with a cephalosporin may modestly add to renal risk. Cefiderocol is renally eliminated, so reduced renal function increases its exposure.
How serious is the interaction between Amikacin and Cefiderocol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and amikacin trough concentrations, and adjust doses to creatinine clearance.
What other medicines interact with Amikacin?
MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
