藥物交互作用
Cefiderocol + Streptomycin
嚴重程度: 中度
Cefiderocol and Streptomycin: moderate interaction.
最後更新
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摘要
Streptomycin is nephrotoxic and ototoxic, and any decline in kidney function raises its exposure. Cefiderocol has little direct nephrotoxicity, so the added risk is modest and mainly from renal changes in sick patients.
用白話說明這項交互作用的意義
Cefiderocol and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefiderocol belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity, with reduced renal clearance of streptomycin if kidney function declines.
處置方式
Monitor serum creatinine and streptomycin levels, and adjust the streptomycin dose to renal function. Watch for hearing loss or vestibular symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Streptomycin 的其他交互作用
Cefiderocol 的其他交互作用
常見問題
Can I take Cefiderocol with Streptomycin?
MediHelp rates the interaction as moderate. Cefiderocol and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Streptomycin is nephrotoxic and ototoxic, and any decline in kidney function raises its exposure. Cefiderocol has little direct nephrotoxicity, so the added risk is modest and mainly from renal changes in sick patients.
How serious is the interaction between Cefiderocol and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and streptomycin levels, and adjust the streptomycin dose to renal function. Watch for hearing loss or vestibular symptoms.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
