藥物交互作用
Amlodipine-olmesartan-hydrochlorothiazide + Potassium chloride
嚴重程度: 嚴重
Amlodipine-olmesartan-hydrochlorothiazide and Potassium chloride: major interaction.
最後更新
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摘要
Potassium chloride supplements with an ARB can cause hyperkalemia, especially in renal impairment or diabetes. The thiazide component lowers potassium and may partly counterbalance this, making the net effect unpredictable.
用白話說明這項交互作用的意義
Amlodipine-olmesartan-hydrochlorothiazide and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Potassium chloride belongs to Gastrointestinal Tract.
為什麼會發生
Added potassium load with reduced renal potassium excretion from angiotensin receptor blockade.
處置方式
Monitor serum potassium and creatinine closely after initiation and dose changes. Avoid routine supplementation unless hypokalemia is documented.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amlodipine-olmesartan-hydrochlorothiazide 的其他交互作用
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan 禁忌併用
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
Potassium chloride 的其他交互作用
常見問題
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Potassium chloride?
MediHelp rates the interaction as major. Amlodipine-olmesartan-hydrochlorothiazide and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Potassium chloride supplements with an ARB can cause hyperkalemia, especially in renal impairment or diabetes. The thiazide component lowers potassium and may partly counterbalance this, making the net effect unpredictable.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Potassium chloride?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and creatinine closely after initiation and dose changes. Avoid routine supplementation unless hypokalemia is documented.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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