藥物交互作用
Eplerenone + Potassium chloride
嚴重程度: 禁忌併用
Eplerenone and Potassium chloride: contraindicated interaction.
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摘要
Eplerenone limits renal potassium loss, and potassium chloride supplies additional potassium. The combination can cause severe, life-threatening hyperkalemia.
用白話說明這項交互作用的意義
Eplerenone and Potassium chloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eplerenone belongs to Cardiovascular; Potassium chloride belongs to Gastrointestinal Tract.
為什麼會發生
Additive potassium retention from aldosterone antagonism plus exogenous potassium intake.
處置方式
Do not use potassium supplements with eplerenone in labeled hypertension use; otherwise avoid and monitor potassium closely if clinically unavoidable.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Eplerenone 的其他交互作用
Potassium chloride 的其他交互作用
常見問題
Can I take Eplerenone with Potassium chloride?
MediHelp rates the interaction as contraindicated. Eplerenone and Potassium chloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eplerenone limits renal potassium loss, and potassium chloride supplies additional potassium. The combination can cause severe, life-threatening hyperkalemia.
How serious is the interaction between Eplerenone and Potassium chloride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use potassium supplements with eplerenone in labeled hypertension use; otherwise avoid and monitor potassium closely if clinically unavoidable.
What other medicines interact with Eplerenone?
MediHelp also lists interactions of Eplerenone with, for example, Amiloride, Atazanavir, Clarithromycin. The full list is on the Eplerenone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。