藥物交互作用
Amoxicillin + Tislelizumab
嚴重程度: 中度
Amoxicillin and Tislelizumab: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Antibiotics may alter gut microbiota, and observational data in cancer patients suggest antibiotic exposure around the start of checkpoint inhibitor therapy is associated with poorer outcomes. A causal effect of a single amoxicillin course has not been established.
用白話說明這項交互作用的意義
Amoxicillin and Tislelizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin belongs to Anti Bacterial; Tislelizumab belongs to Oncology.
為什麼會發生
Antibiotic-induced gut dysbiosis may impair immune responses that support checkpoint inhibitor efficacy; the mechanism is not firmly established.
處置方式
Prescribe antibiotics only when clearly indicated and use the shortest effective course, especially around treatment initiation. Monitor tumor response as usual.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amoxicillin 的其他交互作用
Tislelizumab 的其他交互作用
常見問題
Can I take Amoxicillin with Tislelizumab?
MediHelp rates the interaction as moderate. Amoxicillin and Tislelizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antibiotics may alter gut microbiota, and observational data in cancer patients suggest antibiotic exposure around the start of checkpoint inhibitor therapy is associated with poorer outcomes. A causal effect of a single amoxicillin course has not been established.
How serious is the interaction between Amoxicillin and Tislelizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prescribe antibiotics only when clearly indicated and use the shortest effective course, especially around treatment initiation. Monitor tumor response as usual.
What other medicines interact with Amoxicillin?
MediHelp also lists interactions of Amoxicillin with, for example, Methotrexate, Bcg vaccine live, Cholera vaccine. The full list is on the Amoxicillin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
