藥物交互作用
Prednisone + Tislelizumab
嚴重程度: 中度
Prednisone and Tislelizumab: moderate interaction.
最後更新
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摘要
Systemic corticosteroids at higher doses before starting tislelizumab may blunt the immune response needed for its antitumor effect. Corticosteroids remain appropriate for treating immune-related adverse reactions after treatment begins.
用白話說明這項交互作用的意義
Prednisone and Tislelizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Prednisone belongs to Endocrine; Tislelizumab belongs to Oncology.
為什麼會發生
Corticosteroid immunosuppression may counteract T-cell activation produced by PD-1 blockade.
處置方式
Avoid baseline systemic prednisone above about 10 mg daily before starting tislelizumab where possible. Use corticosteroids as needed to treat immune-related adverse reactions.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Tislelizumab 的其他交互作用
Prednisone 的其他交互作用
常見問題
Can I take Prednisone with Tislelizumab?
MediHelp rates the interaction as moderate. Prednisone and Tislelizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids at higher doses before starting tislelizumab may blunt the immune response needed for its antitumor effect. Corticosteroids remain appropriate for treating immune-related adverse reactions after treatment begins.
How serious is the interaction between Prednisone and Tislelizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid baseline systemic prednisone above about 10 mg daily before starting tislelizumab where possible. Use corticosteroids as needed to treat immune-related adverse reactions.
What other medicines interact with Tislelizumab?
MediHelp also lists interactions of Tislelizumab with, for example, Amoxicillin-clavulanic acid, Amoxicillin, Piperacillin-tazobactam. The full list is on the Tislelizumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
