藥物交互作用
Amphotericin b + Cephaloridine
嚴重程度: 嚴重
Amphotericin b and Cephaloridine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in common use. With amphotericin B, the combined renal tubular injury increases the risk of acute kidney injury.
用白話說明這項交互作用的意義
Amphotericin b and Cephaloridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive tubular nephrotoxicity.
處置方式
Avoid the combination and choose a less nephrotoxic antibacterial. If it cannot be avoided, monitor renal function and electrolytes closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amphotericin b 的其他交互作用
常見問題
Can I take Amphotericin b with Cephaloridine?
MediHelp rates the interaction as major. Amphotericin b and Cephaloridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in common use. With amphotericin B, the combined renal tubular injury increases the risk of acute kidney injury.
How serious is the interaction between Amphotericin b and Cephaloridine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a less nephrotoxic antibacterial. If it cannot be avoided, monitor renal function and electrolytes closely.
What other medicines interact with Amphotericin b?
MediHelp also lists interactions of Amphotericin b with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Amphotericin b page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
