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藥物交互作用

Amphotericin b + Cidofovir

嚴重程度: 禁忌併用

Amphotericin b and Cidofovir: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Amphotericin B and cidofovir can each injure the kidney, so combined exposure heightens the chance of acute kidney injury.

用白話說明這項交互作用的意義

Amphotericin b and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Amphotericin b belongs to Anti Fungals; Cidofovir belongs to Anti Virals.

證據等級: High

為什麼會發生

Additive nephrotoxicity

處置方式

Do not use together; labelling for the nephrotoxic partner prohibits concurrent use. Allow a washout interval when switching.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Amphotericin b 與 Cidofovir 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Amphotericin b with Cidofovir?

MediHelp rates the interaction as contraindicated. Amphotericin b and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Amphotericin B and cidofovir can each injure the kidney, so combined exposure heightens the chance of acute kidney injury.

How serious is the interaction between Amphotericin b and Cidofovir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; labelling for the nephrotoxic partner prohibits concurrent use. Allow a washout interval when switching.

What other medicines interact with Amphotericin b?

MediHelp also lists interactions of Amphotericin b with, for example, Adefovir, Amikacin, Arsenic trioxide. The full list is on the Amphotericin b page.

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