藥物交互作用
Amphotericin b + Capreomycin
嚴重程度: 嚴重
Amphotericin b and Capreomycin: major interaction.
最後更新
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摘要
Both drugs are nephrotoxic, and capreomycin can also cause ototoxicity and electrolyte loss. Together they raise the risk of acute kidney injury and hypokalemia or hypomagnesemia.
用白話說明這項交互作用的意義
Amphotericin b and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive nephrotoxicity through tubular injury and renal electrolyte wasting.
處置方式
Avoid concurrent use where an alternative exists. If unavoidable, monitor serum creatinine, potassium and magnesium frequently and replace electrolytes.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amphotericin b 的其他交互作用
常見問題
Can I take Amphotericin b with Capreomycin?
MediHelp rates the interaction as major. Amphotericin b and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are nephrotoxic, and capreomycin can also cause ototoxicity and electrolyte loss. Together they raise the risk of acute kidney injury and hypokalemia or hypomagnesemia.
How serious is the interaction between Amphotericin b and Capreomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where an alternative exists. If unavoidable, monitor serum creatinine, potassium and magnesium frequently and replace electrolytes.
What other medicines interact with Amphotericin b?
MediHelp also lists interactions of Amphotericin b with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Amphotericin b page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
