藥物交互作用
Anakinra + Etrasimod
嚴重程度: 嚴重
Anakinra and Etrasimod: major interaction.
最後更新
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摘要
Etrasimod reduces circulating lymphocytes, and adding anakinra may further weaken immune defense. Combination use has not been studied, and the lymphocyte effect of etrasimod persists for weeks after stopping.
用白話說明這項交互作用的意義
Anakinra and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anakinra belongs to Musculoskeletal; Etrasimod belongs to Gastrointestinal Tract.
為什麼會發生
Additive immunosuppression from S1P receptor modulation with lymphocyte sequestration and IL-1 blockade.
處置方式
Avoid coadministration where possible, including during the weeks after etrasimod discontinuation; if unavoidable, monitor for infection and lymphocyte counts.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anakinra 的其他交互作用
Etrasimod 的其他交互作用
常見問題
Can I take Anakinra with Etrasimod?
MediHelp rates the interaction as major. Anakinra and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod reduces circulating lymphocytes, and adding anakinra may further weaken immune defense. Combination use has not been studied, and the lymphocyte effect of etrasimod persists for weeks after stopping.
How serious is the interaction between Anakinra and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid coadministration where possible, including during the weeks after etrasimod discontinuation; if unavoidable, monitor for infection and lymphocyte counts.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
