藥物交互作用
Anagrelide + Etrasimod
嚴重程度: 嚴重
Anagrelide and Etrasimod: major interaction.
最後更新
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摘要
Anagrelide can prolong the QT interval and cause tachycardia and palpitations. Etrasimod causes transient slowing of heart rate and AV conduction delay on initiation, and bradycardia increases the risk of torsades de pointes with QT-prolonging drugs.
用白話說明這項交互作用的意義
Anagrelide and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Etrasimod belongs to Gastrointestinal Tract.
為什麼會發生
Additive QT prolongation with etrasimod-induced bradycardia and conduction delay.
處置方式
Obtain a baseline ECG and correct potassium and magnesium before starting. Monitor ECG and heart rate, or consider an alternative agent in patients with other QT risk factors.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anagrelide 的其他交互作用
Etrasimod 的其他交互作用
常見問題
Can I take Anagrelide with Etrasimod?
MediHelp rates the interaction as major. Anagrelide and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anagrelide can prolong the QT interval and cause tachycardia and palpitations. Etrasimod causes transient slowing of heart rate and AV conduction delay on initiation, and bradycardia increases the risk of torsades de pointes with QT-prolonging drugs.
How serious is the interaction between Anagrelide and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium before starting. Monitor ECG and heart rate, or consider an alternative agent in patients with other QT risk factors.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
