藥物交互作用
Anastrozole + Estradiol
嚴重程度: 禁忌併用
Anastrozole and Estradiol: contraindicated interaction.
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本頁的臨床內容僅提供英文版。
摘要
Estradiol opposes anastrozole by restoring the estrogen levels the aromatase inhibitor is meant to suppress. Efficacy in breast cancer may be reduced.
用白話說明這項交互作用的意義
Anastrozole and Estradiol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Anastrozole belongs to Oncology; Estradiol belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism of aromatase inhibitor effect
處置方式
Do not use together; consider non-estrogen alternatives.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Estradiol 的其他交互作用
Anastrozole 的其他交互作用
常見問題
Can I take Anastrozole with Estradiol?
MediHelp rates the interaction as contraindicated. Anastrozole and Estradiol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Estradiol opposes anastrozole by restoring the estrogen levels the aromatase inhibitor is meant to suppress. Efficacy in breast cancer may be reduced.
How serious is the interaction between Anastrozole and Estradiol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; consider non-estrogen alternatives.
What other medicines interact with Estradiol?
MediHelp also lists interactions of Estradiol with, for example, Fezolinetant, Ospemifene, Antithrombin alfa. The full list is on the Estradiol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
