藥物交互作用
Antithrombin iii + Estradiol
嚴重程度: 嚴重
Antithrombin iii and Estradiol: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Estrogens increase thrombotic tendency and may blunt the effect of antithrombin III replacement, increasing the risk of thromboembolism.
用白話說明這項交互作用的意義
Antithrombin iii and Estradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Estradiol raises procoagulant factor levels and lowers antithrombin activity, pharmacodynamically opposing therapy.
處置方式
Avoid estrogen in patients needing antithrombin treatment where possible. If used, monitor antithrombin activity and for thrombosis.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Estradiol 的其他交互作用
常見問題
Can I take Antithrombin iii with Estradiol?
MediHelp rates the interaction as major. Antithrombin iii and Estradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Estrogens increase thrombotic tendency and may blunt the effect of antithrombin III replacement, increasing the risk of thromboembolism.
How serious is the interaction between Antithrombin iii and Estradiol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid estrogen in patients needing antithrombin treatment where possible. If used, monitor antithrombin activity and for thrombosis.
What other medicines interact with Estradiol?
MediHelp also lists interactions of Estradiol with, for example, Anastrozole, Fezolinetant, Ospemifene. The full list is on the Estradiol page.
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