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藥物交互作用

Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal

嚴重程度: 禁忌併用

Anti-thymocyte and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

The intranasal influenza vaccine contains live attenuated virus, which could cause vaccine-strain infection in a patient profoundly immunosuppressed by anti-thymocyte globulin. The immune response to it is also likely to be poor.

用白話說明這項交互作用的意義

Anti-thymocyte and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

證據等級: High

為什麼會發生

Profound T-cell depletion allows replication of live attenuated virus and impairs the immune response.

處置方式

Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Interaction checker for a whole prescription

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常見問題

Can I take Anti-thymocyte with Influenza virus vaccine quadrivalent intranasal?

MediHelp rates the interaction as contraindicated. Anti-thymocyte and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could cause vaccine-strain infection in a patient profoundly immunosuppressed by anti-thymocyte globulin. The immune response to it is also likely to be poor.

How serious is the interaction between Anti-thymocyte and Influenza virus vaccine quadrivalent intranasal?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Anti-thymocyte page.

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