藥物交互作用
Antithrombin alfa + Piperacillin
嚴重程度: 中度
Antithrombin alfa and Piperacillin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Piperacillin can impair platelet function and may add to bleeding risk in patients receiving antithrombin, which is used with heparin. The interaction is mainly theoretical and may be modest.
用白話說明這項交互作用的意義
Antithrombin alfa and Piperacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
High-dose piperacillin impairs platelet aggregation, adding to antithrombin-enhanced anticoagulation.
處置方式
Monitor for bleeding and coagulation parameters such as aPTT or anti-Xa during co-therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Piperacillin 的其他交互作用
常見問題
Can I take Antithrombin alfa with Piperacillin?
MediHelp rates the interaction as moderate. Antithrombin alfa and Piperacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Piperacillin can impair platelet function and may add to bleeding risk in patients receiving antithrombin, which is used with heparin. The interaction is mainly theoretical and may be modest.
How serious is the interaction between Antithrombin alfa and Piperacillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and coagulation parameters such as aPTT or anti-Xa during co-therapy.
What other medicines interact with Piperacillin?
MediHelp also lists interactions of Piperacillin with, for example, Vancomycin, Acetylsalicylic acid, Amikacin. The full list is on the Piperacillin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
