藥物交互作用
Arformoterol + Cisapride
嚴重程度: 嚴重
Arformoterol and Cisapride: major interaction.
最後更新
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摘要
Cisapride prolongs the QT interval, and long-acting beta-agonists such as arformoterol can cause hypokalemia, tachycardia and QT prolongation. The combination increases the risk of ventricular arrhythmias including torsades de pointes.
用白話說明這項交互作用的意義
Arformoterol and Cisapride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Cisapride belongs to Gastrointestinal Tract.
為什麼會發生
Additive QT prolongation with beta-agonist-related hypokalemia and increased heart rate.
處置方式
Avoid the combination if possible and use a non-QT-prolonging prokinetic. If unavoidable, monitor ECG and correct potassium and magnesium.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisapride 的其他交互作用
Arformoterol 的其他交互作用
常見問題
Can I take Arformoterol with Cisapride?
MediHelp rates the interaction as major. Arformoterol and Cisapride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cisapride prolongs the QT interval, and long-acting beta-agonists such as arformoterol can cause hypokalemia, tachycardia and QT prolongation. The combination increases the risk of ventricular arrhythmias including torsades de pointes.
How serious is the interaction between Arformoterol and Cisapride?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible and use a non-QT-prolonging prokinetic. If unavoidable, monitor ECG and correct potassium and magnesium.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
