藥物交互作用
Arformoterol + Fluticasone-vilanterol
嚴重程度: 嚴重
Arformoterol and Fluticasone-vilanterol: major interaction.
最後更新
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摘要
Both products contain a long-acting beta2-agonist, so combining them duplicates therapy and increases beta-adrenergic effects such as tachycardia, tremor, hypokalemia and QT prolongation. The risk of arrhythmia is greater than with a single agent.
用白話說明這項交互作用的意義
Arformoterol and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Fluticasone-vilanterol belongs to Respiratory.
為什麼會發生
Duplicate beta2-adrenergic agonism producing additive cardiovascular and hypokalemic effects.
處置方式
Avoid concurrent use of two long-acting beta2-agonists; keep only one LABA and stop the other. Monitor heart rate, ECG and serum potassium if overlap occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fluticasone-vilanterol 的其他交互作用
Arformoterol 的其他交互作用
常見問題
Can I take Arformoterol with Fluticasone-vilanterol?
MediHelp rates the interaction as major. Arformoterol and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both products contain a long-acting beta2-agonist, so combining them duplicates therapy and increases beta-adrenergic effects such as tachycardia, tremor, hypokalemia and QT prolongation. The risk of arrhythmia is greater than with a single agent.
How serious is the interaction between Arformoterol and Fluticasone-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two long-acting beta2-agonists; keep only one LABA and stop the other. Monitor heart rate, ECG and serum potassium if overlap occurs.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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