藥物交互作用
Arformoterol + Desipramine
嚴重程度: 嚴重
Arformoterol and Desipramine: major interaction.
最後更新
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摘要
Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.
用白話說明這項交互作用的意義
Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Desipramine belongs to Central Nervous System.
為什麼會發生
Additive adrenergic stimulation and QT prolongation.
處置方式
Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Desipramine 的其他交互作用
Arformoterol 的其他交互作用
常見問題
Can I take Arformoterol with Desipramine?
MediHelp rates the interaction as major. Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.
How serious is the interaction between Arformoterol and Desipramine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.
What other medicines interact with Desipramine?
MediHelp also lists interactions of Desipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Desipramine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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