藥物交互作用
Arsenic trioxide + Fluphenazine
嚴重程度: 禁忌併用
Arsenic trioxide and Fluphenazine: contraindicated interaction.
最後更新
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摘要
Arsenic trioxide causes marked QT prolongation and torsades de pointes, and fluphenazine adds further QT risk. Labeling advises avoiding other QT-prolonging drugs.
用白話說明這項交互作用的意義
Arsenic trioxide and Fluphenazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Arsenic trioxide belongs to Oncology; Fluphenazine belongs to Central Nervous System.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Avoid concurrent use and choose a non-QT-prolonging antipsychotic. Keep potassium and magnesium normal and monitor ECG throughout arsenic therapy.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Fluphenazine 的其他交互作用
Arsenic trioxide 的其他交互作用
常見問題
Can I take Arsenic trioxide with Fluphenazine?
MediHelp rates the interaction as contraindicated. Arsenic trioxide and Fluphenazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Arsenic trioxide causes marked QT prolongation and torsades de pointes, and fluphenazine adds further QT risk. Labeling advises avoiding other QT-prolonging drugs.
How serious is the interaction between Arsenic trioxide and Fluphenazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-QT-prolonging antipsychotic. Keep potassium and magnesium normal and monitor ECG throughout arsenic therapy.
What other medicines interact with Fluphenazine?
MediHelp also lists interactions of Fluphenazine with, for example, Dofetilide, Ibutilide, Pimozide. The full list is on the Fluphenazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
